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Pharmaceutical Purified water

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Pharmaceutical purified water plays a central role in drug production, widely used as a solvent, ingredient, and equipment cleaning agent. Its quality is directly linked to the final quality of drugs and patient safety. Purified water is an essential raw material in the pharmaceutical production process, and its quality can directly impact both drug quality and safety. Strict microbial control of purified water systems is a core requirement of Good Manufacturing Practice (GMP). Among the various microbial control methods, ultraviolet (UV) disinfection and ozone (O3) disinfection are widely used due to their respective characteristics.

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UV disinfection devices offer flexibility and can be installed at various key points in a purified water system:

UV Total Organic Carbon (TOC) Reduction Device

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Installed in the polishing unit of purified water preparation to protect subsequent units from organic contamination or to further remove residual organic matter.

UV Residual Chlorine Removal Unit

Installed after the activated carbon filter and before the reverse osmosis membrane, it removes residual chlorine from the raw water or pretreatment process to prevent oxidation and damage to the reverse osmosis membrane.

UV Ozone Decomposition Unit

After ozone disinfection, residual ozone in the water needs to be removed before the point of use. Ultraviolet light effectively catalyzes the decomposition of ozone, converting it to oxygen, preventing residual ozone from affecting subsequent processes or the final product.

Ozone Disinfection

Ozone is primarily used for microbial control in purified water storage and distribution systems, particularly for the prevention and removal of biofilms. High-concentration ozone water is regularly injected into the system and circulated for a period of time to kill microorganisms within the system (including storage tanks and pipe linings) and destroy any biofilms that have formed.

·Continuous Low-Concentration Disinfection: A low concentration of ozone (e.g., tens of ppb) is maintained in the purified water storage tanks and distribution system to continuously inhibit microbial growth and biofilm formation.

Ozone disinfection has a strong inactivating effect on bacteria, bacterial spores, viruses, and fungi. Ozone has a certain solubility in water, and as a gas, it can theoretically diffuse into every corner of a water system, including areas difficult to reach with traditional liquid disinfectants, such as tank headspaces and valve blind spots. This allows ozone to achieve a more comprehensive range of effects when used for system-wide disinfection, compared to ultraviolet light, which is only effective on the water flow.

In pharmaceutical purified water systems, a single disinfection technology often cannot perfectly address all challenges. Ultraviolet (UV) and ozone (O3) each have unique advantages and limitations. Combining them to form a synergistic strategy is a common and effective method in the industry to improve microbial control and optimize system performance.

This combined approach uses ozone as the primary system disinfectant and UV for ozone removal and terminal protection.

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Municipal Municipal Wastewater Municipal water supply Recycled Water Reuse Township water supply and drainage Industrial Park New pollutant control Water ecological restoration project

Industry Pretreatment of industrial high-difficulty wastewater Pesticide Industry API pharmaceuticals Chemical waste salt purification Food & Beverage Industry Pharmaceutical Purified water Chip Fabrication Oilfield reinjection water Industrial zero emissions

Commercial Secondary water supply Pool & Aquarium High-quality drinking water POE/POU Aquaculture Cooling Circulating water Laboratory applications

UV-AOPs Wastewater Biodegradability Pretreatment of highly toxic industrial wastewater Chemical active agents Cyanide Organic Complexes

Craftsmanship UV disinfection UV photolysis UV Advanced Oxidation Reverse Osmosis Alternative to pasteurization UV photochemical reaction Ozone oxidation

Resource Recycling waste plastics Construction waste Renovation waste

Municipal WSH UV Disinfection System WTV UV Disinfection Vertical System ZL UV Disinfection System Clear Medium Pressure UV Disinfection System MOL Ceramic Plate CD Ozone Generator UV-AOP Advanced Oxidation System D.FITE Cloth Filter

Industry ZL UV Disinfection System Clear Medium Pressure UV Disinfection System UV-AOP Advanced Oxidation Extrem Medium Pressure UV Disinfection System EX-U UV Sterilizer EX-UPW-TOC UV TOC System MOM Ceramic Plate CD Ozone Generator MOS Ceramic Plate CD Ozone Generator UV-Fenton UV-Oxidation

Commercial EX-L UV Sterilizer EX-U UV Sterilizer ZL UV Disinfection System CLEAR Medium pressure UV Disinfection System OneUV UV Sterilizer Extrem Medium pressure UV Disinfection System UV-AOP Advanced Oxidation MOS Ceramic Plate CD Ozone Generator COG Ceramic Plate CD Ozone Generator

Photochemistry UV-Fenton Medium-pressure UV-Oxidation UV Photolysis Pasteurization UV Alternatives UV Photocatalysis Low Pressure UV-Oxidation

Resource Recycling AI Optical Sorter Al high-speed sorting robot AI heavy-duty sorting robot

Others SATBR Integrated Wastewater Treatment System D.FITE Cloth Filter Modular Wastewater Treatment System ModuOzone Ceramic Plate CD Ozone Generator

After-Sales Services Spare parts replacement Product Repair System Support Renovation Regular maintenance Software Upgrade

Technical Support Process Support Product Training Research & Development Small Test Pilotscale experiment Online dose monitoring UV dose design

Channel Services Municipal Industry Business OEM

Spare parts Low Pressure lamps Low Pressure Amalgam Lamps Medium Pressure Mercury Lamp VUV Low-pressure Mercury Lamp（185nm） Quartz sleeve Ballasts UV Intensity Sensor UV transmittance tester Sealing accessories Other Spare parts replacement

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